Selected Publications

Bao EL*, Nandakumar SK*, Liao X*, Bick A, Karjalainen J, Tabaka M, Gan OI, Havulinna A, Kiiskinen TT, Lareau CA, de Lapuente Portilla AL, Li B, Emdin C, Codd V, Nelson CP, Walker CJ, Churchhouse C, de la Chapelle A, Klein DE, Nilsson B, Wilson P, Cho K, Pyarajan S, Gaziano MJ, Samani NJ, FinnGen, 23andMe Research Team, Million Veteran Program, Regev A, Palotie A, Neale BM, Dick JE, Natarajan P, O’Donnell C, Daly MJ, Milyavsky M, Kathiresan S and Sankaran VG. Inherited myeloproliferative neoplasm risk impacts hematopoietic stem cells. Nature. (2020)

Bick A*, Weinstock J*, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, …. Kitzman JO, Lander ES, Engreitz J, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P. Inherited causes of clonal hematopoiesis in 97,691 whole genomes. Nature. (2020)

Nandakumar SK*, Liao X*, Sankaran VG. In The Blood: Connecting Variant to Function In Human Hematopoiesis. Trends in Genetics. (2020)

Verboon JM, Mahmut D, Kim AR, Nakamura M, Abdulhay NJ, Nandakumar SK, Gupta N, Akie TE, Geddis AE, Manes B, Kapp ME, Hofmann I, Gabriel SB, Klein DE, Williams DA, Frangoul HA, Parkhurst SM, Crane GM, Cantor AB, and Sankaran VG. Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction. Journal of Clinical Immunology (2020)

Nandakumar SK*, McFarland SK*, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, Sankaran VG. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. eLife. (2019)

Ludwig LS*, Lareau CA*, Bao EL, Nandakumar SK, Christoph Muus, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG. Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Reports. (2019)

Guo MH*, Nandakumar SK*, Ulirsch JC, Zekavat SM, Buenrostro JD, Natarajan P, Salem RM, Chiarle R, Mitt M, Kals M, Parn K, Fischer K, Milani L, Magi R, Palta P, Gabriel SB, Metspalu A, Lander ES, Kathiresan S, Hirschhorn JN, Esko T, Sankaran VG. Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. PNAS. (2017)

Ulirsch JC*, Nandakumar SK*, Wang L, Giani FC, Zhang X, Rogov P, Melnikov A, McDonel P, Do R, Mikkelsen TS, Sankaran VG. Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits. Cell. (2016)

Nandakumar SK, Johnson K, Throm SL, Pestina TI, Neale G, Persons DA. Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice. Experimental hematology. (2015)